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Cyclic Neutropenia is a stem cell disease, which is characterised by cyclic fluctuations in leukocyte numbers, especially the neutrophils.
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Specifiche
| Breeds | |
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| Gene | |
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| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
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| Chromosome | |
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Informazioni generali
Cyclic Neutropenia is a stem cell disease, which is characterised by cyclic fluctuations in leukocyte numbers, especially the neutrophils.
In dogs the disease is also known as cyclic hematopoiesis or Grey/Gray Collie Syndrom. In humans known as Hermansky-Pudlak Syndrome 2 (HPS-2).
Caratteristiche cliniche
Affected animals have an associated coat colour dilution, causing a gray coat colour. The cyclic neutropenia is associated with symptoms as recurrent fever, anorexia and severe - often life threathening - infections.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 12897784
Omia ID: 248