€57,48 €47,50 IVA esclusa
Hypophosphatasia is a severe skeletal disorder which affects the Karelian Bear Dog, and causes poor bone structure and retarded growth.
Working days 10
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Hypophosphatasia is a severe skeletal disorder which affects the Karelian Bear Dog, and causes poor bone structure and retarded growth. It is caused by a recessive mutation to the gene ALPL.
Caratteristiche cliniche
Affected puppies start falling behind in growth with respect to their littermates by the age of 7 to 10 weeks. They also have difficulty moving, with muscle weakness, a crouched stance and deformed bones and joints. The affected dog may die within the first 10 weeks of life; if not, euthanasia on humane grounds may be necessary due to the severity of symptoms.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 30700765
Omia ID: 2162