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Leukoencephalomyeolopathy (LEMP) is a neurological disease that affects the central nervous system, affecting coordination and gait.
Working days 10
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Leukoencephalomyeolopathy (LEMP) is a neurological disease that affects the central nervous system, affecting coordination and gait. The variant of the disease in this test occurs in the Great Dane and Rottweiler, and is caused by a recessive mutation to the gene LEMP. Another variant has been observed in the Leonberger.
Caratteristiche cliniche
Onset of LEMP occurs in juvenile dogs. Symptoms include slowly worsening gait abnormalities such as paw "knuckling", dragging of the paws, and hypermetria (overstepping while walking) of the front legs. The disease progresses over a matter of months.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 29643404
Omia ID: 1788