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American Staffordshire Terrier Juvenile Laryngeal Paralysis and Polyneuropathy (ALPP) is a severe neurological disorder characterized by difficulty breathing and loss of muscle coordination.
Working days 25
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Tampone, Sangue in EDTA, Sangue in Eparina, Seme, Tessuto |
| Mode of Inheritance | |
| Also known as |
Informazioni generali
American Staffordshire Terrier Juvenile Laryngeal Paralysis and Polyneuropathy (ALPP) is a severe neurological disorder characterized by difficulty breathing and loss of muscle coordination. This variant, observed in the American Staffordshire Terrier, is caused by an autosomal recessive genetic mutation.
Caratteristiche cliniche
Affected dogs typically present around 3 months of age with laryngeal paralysis and respiratory distress. Loss of movement coordination often develops a few months to a few years later. Additional symptoms may include limb weakness, ataxia (loss of coordination), progressive muscle atrophy, altered barking (dysphonia), vomiting, and swallowing difficulties. In some cases, symptoms may stabilize, although episodes of ataxia and swallowing difficulties may persist. The dogs of which symptoms stabilize, seem to lead an almost normal life.
Informazioni aggiuntive
Questo test viene eseguito da un laboratorio esterno. CombiBreed si occupa della mediazione tra voi come clienti e il laboratorio esterno. In questo caso, CombiBreed non può essere ritenuta responsabile per il comportamento del cliente e/o dell'appaltatore.
Riferimenti
Pubmed ID: Unpublished data University of Missouri
Omia ID: 1970