57,48 47,50 IVA esclusa

H412

Canine Complement 3 (C3) deficiency is a metabolic disorder in the Brittany Spaniel that leaves affected dogs vulnerable to infections.

Working days 10

Specifiche

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

Informazioni generali

Canine Complement 3 (C3) deficiency is a metabolic disorder in the Brittany Spaniel that leaves affected dogs vulnerable to infections. The disorder is caused by a recessive mutation to the C3 gene.

Caratteristiche cliniche

Affected dogs are vulnerable to to various kidney and urinary tract diseases. Particularly when young, they are likely to experience recurrent bacterial infections such as pneumonia, urinary tract infections and uterine tract infections. They are also more prone to Membranoproliferative Glomerulonephritis (MPGN), which can cause kidney damage and kidney failure.

Informazioni aggiuntive

Riferimenti

Pubmed ID: 9510185

Omia ID: 155

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