€57,48 €47,50 IVA esclusa
Multi Drug Resistance 1 (MDR1), sometimes known as Ivermectin Sensitivity, is a disorder that affects the blood-brain barrier.
Working days 10
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Tampone, Sangue in EDTA, Sangue in Eparina, Seme, Tessuto |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Multi Drug Resistance 1 (MDR1), sometimes known as Ivermectin Sensitivity, is a disorder that affects the blood-brain barrier. As a result, affected animals can be in effect poisoned when given certain drugs as part of standard veterinary procedures. In cats, a variant of the disease is caused by a recessive mutation to the gene ABCB1.
It is estimated that this mutation occurs in approximately 4% of domestic cats.
Caratteristiche cliniche
È probabile che i gatti affetti manifestino reazioni avverse (tossicità del sistema nervoso centrale) ai farmaci substrati della glicoproteina P come l'ivermectina, l'imidacloprid e la selamectina.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 25660379
Omia ID: 1402