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Myeloperoxidase Deficiency (MPOD) is a disorder affecting white blood cells, observed in the Italian Hound (e.
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Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Myeloperoxidase Deficiency (MPOD) is a disorder affecting white blood cells, observed in the Italian Hound (e.g. Italian Greyhound, Segugio Italiano). It is caused by a recessive mutation to the gene MPO.
Caratteristiche cliniche
Myeloperoxidase Deficiency is primarily evident in blood analysis such as complete blood count perox. Affected white blood cells, normally stained as MPO-positive, will not be stained and cluster align in the unstained cell area.
The disorder itself is believed to lead to lead to an increased vulnerability to infections.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 27296514
Omia ID: 2028